Medicine Quality: the harder you look the worse it gets
The Minilab protocol is an excellent method of identifying falsified medicines, and two per cent (18 out of 899 samples) were falsified. However, as the data in this paper show, it considerably underestimates (by roughly 4.5%) the amount of substandard medicines in the market (roughly 12 per cent), especially among medicines made by Indian companies. In addition to considerable patient death, substandard antimicrobial medicines are likely to drive drug resistance. Policymakers should redouble efforts to identify and combat such medicines.
Full Text:Subscribers Only
Bate, R., Jin, G.Z., & Mathur, A. (2012). Counterfeit or substandard? Assessing price and non price signals of drug quality. (NBER Working Paper No. 18073). Cambridge, MA: National Bureau of Economic Research.
——— . (2015). Falsified or substandard? Assessing price and non-price signals of drug quality. Journal of Economics and Management Strategy, 24(24).
Bate, R., Jin, G.Z., Mathur, A., & Attaran, A. (2016). Poor-quality drugs and global trade: a pilot study. American Journal of Heath Economics, 2(3), 373-398.
Caudron, J.M., Ford, N., Henkens, M., Mace, C., Kiddle-Monroe, R., & Pin, J. (2008). Substandard medicines in resource-poor settings: a problem that can no longer be ignored. Tropical Medicine & International Health, 13(8).
Cockburn, R., Newton, P.N., Agyarko, E.K., Akunyili, D., & White, N.J. (2005). The Global Threat of Counterfeit Drugs: Why Industry and Governments Must Communicate the Dangers. Plos Med, 2(4).
Institute of Medicine (2013). Countering the Problem of Falsified and Substandard Drugs. Washington, DC: National Academy of Sciences.
Jähnke, R.W.O., Küsters, G., & Fleischer, K. Low-cost quality assurance of medicines using the GPHF-Minilab. Drug Information Journal, 35: 941-945.
Nayyar, Gaurvika M L; Breman, Joel G; Newton, Paul N; Herrington, James. “Poor-quality antimalarial drugs in southeast Asia and sub-Saharan Africa.” The Lancet. Vol. 12, June 2012.
Renschler, John P. Kelsey M. Walters, Paul N. Newton, and Ramanan Laxminarayan Estimated Under-Five Deaths Associated with Poor-Quality Antimalarials in Sub-Saharan Africa Am. J. Trop. Med. Hyg., 92(Suppl 6), 2015, pp. 119–126
- There are currently no refbacks.